Diversity of Middle East respiratory syndrome coronaviruses in 109 dromedary camels based on full-genome sequencing, Abu Dhabi, United Arab Emirates
Identifieur interne : 000E23 ( Main/Exploration ); précédent : 000E22; suivant : 000E24Diversity of Middle East respiratory syndrome coronaviruses in 109 dromedary camels based on full-genome sequencing, Abu Dhabi, United Arab Emirates
Auteurs : Mohammed Farouk Yusof ; Krista Queen [États-Unis] ; Yassir Mohammed Eltahir ; Clinton R. Paden [États-Unis] ; Zulaikha Mohamed Abdel Hameed Al Hammadi ; Ying Tao [États-Unis] ; Yan Li [États-Unis] ; Abdelmalik Ibrahim Khalafalla ; Mang Shi [Australie] ; Jing Zhang [États-Unis] ; Muzammil Sayed Ahmed Elhaj Mohamed ; Mahmud Hamed Abd Elaal Ahmed ; Ihsaan Abdulwahab Azeez ; Oum Keltoum Bensalah ; Ziyada Swar Eldahab ; Farida Ismail Al Hosani ; Susan I. Gerber [États-Unis] ; Aron J. Hall [États-Unis] ; Suxiang Tong [États-Unis] ; Salama Suhail Al MuhairiSource :
- Emerging Microbes & Infections [ 2222-1751 ] ; 2017.
Descripteurs français
- KwdFr :
- Analyse de regroupements, Analyse de séquence d'ADN, Animaux, Chameaux (virologie), Coronavirus du syndrome respiratoire du Moyen-Orient (), Coronavirus du syndrome respiratoire du Moyen-Orient (génétique), Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification), Femelle, Glycoprotéine de spicule des coronavirus (génétique), Génome viral, Génotype, Mâle, Phylogénie, Recombinaison génétique, Variation génétique, Émirats arabes unis.
- MESH :
- génétique : Coronavirus du syndrome respiratoire du Moyen-Orient, Glycoprotéine de spicule des coronavirus.
- isolement et purification : Coronavirus du syndrome respiratoire du Moyen-Orient.
- virologie : Chameaux.
- Analyse de regroupements, Analyse de séquence d'ADN, Animaux, Coronavirus du syndrome respiratoire du Moyen-Orient, Femelle, Génome viral, Génotype, Mâle, Phylogénie, Recombinaison génétique, Variation génétique, Émirats arabes unis.
English descriptors
- KwdEn :
- Animals, Camelus (virology), Cluster Analysis, Female, Genetic Variation, Genome, Viral, Genotype, Male, Middle East Respiratory Syndrome Coronavirus (classification), Middle East Respiratory Syndrome Coronavirus (genetics), Middle East Respiratory Syndrome Coronavirus (isolation & purification), Phylogeny, Recombination, Genetic, Sequence Analysis, DNA, Spike Glycoprotein, Coronavirus (genetics), United Arab Emirates.
- MESH :
- chemical , genetics : Spike Glycoprotein, Coronavirus.
- classification : Middle East Respiratory Syndrome Coronavirus.
- genetics : Middle East Respiratory Syndrome Coronavirus.
- isolation & purification : Middle East Respiratory Syndrome Coronavirus.
- virology : Camelus.
- Animals, Cluster Analysis, Female, Genetic Variation, Genome, Viral, Genotype, Male, Phylogeny, Recombination, Genetic, Sequence Analysis, DNA, United Arab Emirates.
Abstract
Middle East respiratory syndrome coronavirus (MERS-CoV) was identified on the Arabian Peninsula in 2012 and is still causing cases and outbreaks in the Middle East. When MERS-CoV was first identified, the closest related virus was in bats; however, it has since been recognized that dromedary camels serve as a virus reservoir and potential source for human infections. A total of 376 camels were screened for MERS-Cov at a live animal market in the Eastern Region of the Emirate of Abu Dhabi, UAE. In all, 109 MERS-CoV-positive camels were detected in week 1, and a subset of positive camels were sampled again weeks 3 through 6. A total of 126 full and 3 nearly full genomes were obtained from 139 samples. Spike gene sequences were obtained from 5 of the 10 remaining samples. The camel MERS-CoV genomes from this study represent 3 known and 2 potentially new lineages within clade B. Within lineages, diversity of camel and human MERS-CoV sequences are intermixed. We identified sequences from market camels nearly identical to the previously reported 2015 German case who visited the market during his incubation period. We described 10 recombination events in the camel samples. The most frequent recombination breakpoint was the junctions between ORF1b and S. Evidence suggests MERS-CoV infection in humans results from continued introductions of distinct MERS-CoV lineages from camels. This hypothesis is supported by the camel MERS-CoV genomes sequenced in this study. Our study expands the known repertoire of camel MERS-CoVs circulating on the Arabian Peninsula.
Url:
DOI: 10.1038/emi.2017.89
PubMed: 29116217
PubMed Central: 5717090
Affiliations:
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Paden</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Division of Viral Diseases, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention</institution>, Atlanta, GA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="2"><nlm:aff id="aff3"><institution>Oak Ridge Associated Universities Fellow</institution>, Oak Ridge, TN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>, Oak Ridge, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Al Hammadi, Zulaikha Mohamed Abdel Hameed" sort="Al Hammadi, Zulaikha Mohamed Abdel Hameed" uniqKey="Al Hammadi Z" first="Zulaikha Mohamed Abdel Hameed" last="Al Hammadi">Zulaikha Mohamed Abdel Hameed Al Hammadi</name><affiliation><nlm:aff id="aff1"><institution>Abu Dhabi Food Control Authority</institution>, Abu Dhabi,<country>UAE</country></nlm:aff><wicri:noCountry code="nlm country">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Tao, Ying" sort="Tao, Ying" uniqKey="Tao Y" first="Ying" last="Tao">Ying Tao</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Division of Viral Diseases, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention</institution>, Atlanta, GA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Division of Viral Diseases, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention</institution>, Atlanta, GA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Khalafalla, Abdelmalik Ibrahim" sort="Khalafalla, Abdelmalik Ibrahim" uniqKey="Khalafalla A" first="Abdelmalik Ibrahim" last="Khalafalla">Abdelmalik Ibrahim Khalafalla</name><affiliation><nlm:aff id="aff1"><institution>Abu Dhabi Food Control Authority</institution>, Abu Dhabi,<country>UAE</country></nlm:aff><wicri:noCountry code="nlm country">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Shi, Mang" sort="Shi, Mang" uniqKey="Shi M" first="Mang" last="Shi">Mang Shi</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>University of Sydney</institution>, Sydney, NSW,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Jing" sort="Zhang, Jing" uniqKey="Zhang J" first="Jing" last="Zhang">Jing Zhang</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Division of Viral Diseases, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention</institution>, Atlanta, GA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>IHRC Inc.</institution>, Atlanta, GA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mohamed, Muzammil Sayed Ahmed Elhaj" sort="Mohamed, Muzammil Sayed Ahmed Elhaj" uniqKey="Mohamed M" first="Muzammil Sayed Ahmed Elhaj" last="Mohamed">Muzammil Sayed Ahmed Elhaj Mohamed</name><affiliation><nlm:aff id="aff1"><institution>Abu Dhabi Food Control Authority</institution>, Abu Dhabi,<country>UAE</country></nlm:aff><wicri:noCountry code="nlm country">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Abd Elaal Ahmed, Mahmud Hamed" sort="Abd Elaal Ahmed, Mahmud Hamed" uniqKey="Abd Elaal Ahmed M" first="Mahmud Hamed" last="Abd Elaal Ahmed">Mahmud Hamed Abd Elaal Ahmed</name><affiliation><nlm:aff id="aff1"><institution>Abu Dhabi Food Control Authority</institution>, Abu Dhabi,<country>UAE</country></nlm:aff><wicri:noCountry code="nlm country">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Azeez, Ihsaan Abdulwahab" sort="Azeez, Ihsaan Abdulwahab" uniqKey="Azeez I" first="Ihsaan Abdulwahab" last="Azeez">Ihsaan Abdulwahab Azeez</name><affiliation><nlm:aff id="aff1"><institution>Abu Dhabi Food Control Authority</institution>, Abu Dhabi,<country>UAE</country></nlm:aff><wicri:noCountry code="nlm country">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Bensalah, Oum Keltoum" sort="Bensalah, Oum Keltoum" uniqKey="Bensalah O" first="Oum Keltoum" last="Bensalah">Oum Keltoum Bensalah</name><affiliation><nlm:aff id="aff1"><institution>Abu Dhabi Food Control Authority</institution>, Abu Dhabi,<country>UAE</country></nlm:aff><wicri:noCountry code="nlm country">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Eldahab, Ziyada Swar" sort="Eldahab, Ziyada Swar" uniqKey="Eldahab Z" first="Ziyada Swar" last="Eldahab">Ziyada Swar Eldahab</name><affiliation><nlm:aff id="aff6"><institution>Abu Dhabi Food Control Authority</institution>, Al Ain,<country>UAE</country></nlm:aff><wicri:noCountry code="nlm country">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Al Hosani, Farida Ismail" sort="Al Hosani, Farida Ismail" uniqKey="Al Hosani F" first="Farida Ismail" last="Al Hosani">Farida Ismail Al Hosani</name><affiliation><nlm:aff id="aff7"><institution>Health Authority of Abu Dhabi</institution>, Abu Dhabi,<country>UAE</country></nlm:aff><wicri:noCountry code="nlm country">UAE</wicri:noCountry></affiliation></author><author><name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I" last="Gerber">Susan I. Gerber</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Division of Viral Diseases, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention</institution>, Atlanta, GA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hall, Aron J" sort="Hall, Aron J" uniqKey="Hall A" first="Aron J" last="Hall">Aron J. Hall</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Division of Viral Diseases, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention</institution>, Atlanta, GA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tong, Suxiang" sort="Tong, Suxiang" uniqKey="Tong S" first="Suxiang" last="Tong">Suxiang Tong</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Division of Viral Diseases, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention</institution>, Atlanta, GA,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Al Muhairi, Salama Suhail" sort="Al Muhairi, Salama Suhail" uniqKey="Al Muhairi S" first="Salama Suhail" last="Al Muhairi">Salama Suhail Al Muhairi</name><affiliation><nlm:aff id="aff1"><institution>Abu Dhabi Food Control Authority</institution>, Abu Dhabi,<country>UAE</country></nlm:aff><wicri:noCountry code="nlm country">UAE</wicri:noCountry></affiliation></author></analytic><series><title level="j">Emerging Microbes & Infections</title><idno type="eISSN">2222-1751</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Camelus (virology)</term><term>Cluster Analysis</term><term>Female</term><term>Genetic Variation</term><term>Genome, Viral</term><term>Genotype</term><term>Male</term><term>Middle East Respiratory Syndrome Coronavirus (classification)</term><term>Middle East Respiratory Syndrome Coronavirus (genetics)</term><term>Middle East Respiratory Syndrome Coronavirus (isolation & purification)</term><term>Phylogeny</term><term>Recombination, Genetic</term><term>Sequence Analysis, DNA</term><term>Spike Glycoprotein, Coronavirus (genetics)</term><term>United Arab Emirates</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Analyse de regroupements</term><term>Analyse de séquence d'ADN</term><term>Animaux</term><term>Chameaux (virologie)</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient ()</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient (génétique)</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification)</term><term>Femelle</term><term>Glycoprotéine de spicule des coronavirus (génétique)</term><term>Génome viral</term><term>Génotype</term><term>Mâle</term><term>Phylogénie</term><term>Recombinaison génétique</term><term>Variation génétique</term><term>Émirats arabes unis</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Spike Glycoprotein, Coronavirus</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term><term>Glycoprotéine de spicule des coronavirus</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Chameaux</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Camelus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cluster Analysis</term><term>Female</term><term>Genetic Variation</term><term>Genome, Viral</term><term>Genotype</term><term>Male</term><term>Phylogeny</term><term>Recombination, Genetic</term><term>Sequence Analysis, DNA</term><term>United Arab Emirates</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse de regroupements</term><term>Analyse de séquence d'ADN</term><term>Animaux</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term><term>Femelle</term><term>Génome viral</term><term>Génotype</term><term>Mâle</term><term>Phylogénie</term><term>Recombinaison génétique</term><term>Variation génétique</term><term>Émirats arabes unis</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Middle East respiratory syndrome coronavirus (MERS-CoV) was identified on the Arabian Peninsula in 2012 and is still causing cases and outbreaks in the Middle East. When MERS-CoV was first identified, the closest related virus was in bats; however, it has since been recognized that dromedary camels serve as a virus reservoir and potential source for human infections. A total of 376 camels were screened for MERS-Cov at a live animal market in the Eastern Region of the Emirate of Abu Dhabi, UAE. In all, 109 MERS-CoV-positive camels were detected in week 1, and a subset of positive camels were sampled again weeks 3 through 6. A total of 126 full and 3 nearly full genomes were obtained from 139 samples. Spike gene sequences were obtained from 5 of the 10 remaining samples. The camel MERS-CoV genomes from this study represent 3 known and 2 potentially new lineages within clade B. Within lineages, diversity of camel and human MERS-CoV sequences are intermixed. We identified sequences from market camels nearly identical to the previously reported 2015 German case who visited the market during his incubation period. We described 10 recombination events in the camel samples. The most frequent recombination breakpoint was the junctions between ORF1b and S. Evidence suggests MERS-CoV infection in humans results from continued introductions of distinct MERS-CoV lineages from camels. This hypothesis is supported by the camel MERS-CoV genomes sequenced in this study. Our study expands the known repertoire of camel MERS-CoVs circulating on the Arabian Peninsula.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Australie</li><li>États-Unis</li></country><region><li>Tennessee</li></region></list><tree><noCountry><name sortKey="Abd Elaal Ahmed, Mahmud Hamed" sort="Abd Elaal Ahmed, Mahmud Hamed" uniqKey="Abd Elaal Ahmed M" first="Mahmud Hamed" last="Abd Elaal Ahmed">Mahmud Hamed Abd Elaal Ahmed</name><name sortKey="Al Hammadi, Zulaikha Mohamed Abdel Hameed" sort="Al Hammadi, Zulaikha Mohamed Abdel Hameed" uniqKey="Al Hammadi Z" first="Zulaikha Mohamed Abdel Hameed" last="Al Hammadi">Zulaikha Mohamed Abdel Hameed Al Hammadi</name><name sortKey="Al Hosani, Farida Ismail" sort="Al Hosani, Farida Ismail" uniqKey="Al Hosani F" first="Farida Ismail" last="Al Hosani">Farida Ismail Al Hosani</name><name sortKey="Al Muhairi, Salama Suhail" sort="Al Muhairi, Salama Suhail" uniqKey="Al Muhairi S" first="Salama Suhail" last="Al Muhairi">Salama Suhail Al Muhairi</name><name sortKey="Azeez, Ihsaan Abdulwahab" sort="Azeez, Ihsaan Abdulwahab" uniqKey="Azeez I" first="Ihsaan Abdulwahab" last="Azeez">Ihsaan Abdulwahab Azeez</name><name sortKey="Bensalah, Oum Keltoum" sort="Bensalah, Oum Keltoum" uniqKey="Bensalah O" first="Oum Keltoum" last="Bensalah">Oum Keltoum Bensalah</name><name sortKey="Eldahab, Ziyada Swar" sort="Eldahab, Ziyada Swar" uniqKey="Eldahab Z" first="Ziyada Swar" last="Eldahab">Ziyada Swar Eldahab</name><name sortKey="Eltahir, Yassir Mohammed" sort="Eltahir, Yassir Mohammed" uniqKey="Eltahir Y" first="Yassir Mohammed" last="Eltahir">Yassir Mohammed Eltahir</name><name sortKey="Khalafalla, Abdelmalik Ibrahim" sort="Khalafalla, Abdelmalik Ibrahim" uniqKey="Khalafalla A" first="Abdelmalik Ibrahim" last="Khalafalla">Abdelmalik Ibrahim Khalafalla</name><name sortKey="Mohamed, Muzammil Sayed Ahmed Elhaj" sort="Mohamed, Muzammil Sayed Ahmed Elhaj" uniqKey="Mohamed M" first="Muzammil Sayed Ahmed Elhaj" last="Mohamed">Muzammil Sayed Ahmed Elhaj Mohamed</name><name sortKey="Yusof, Mohammed Farouk" sort="Yusof, Mohammed Farouk" uniqKey="Yusof M" first="Mohammed Farouk" last="Yusof">Mohammed Farouk Yusof</name></noCountry><country name="États-Unis"><noRegion><name sortKey="Queen, Krista" sort="Queen, Krista" uniqKey="Queen K" first="Krista" last="Queen">Krista Queen</name></noRegion><name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I" last="Gerber">Susan I. Gerber</name><name sortKey="Hall, Aron J" sort="Hall, Aron J" uniqKey="Hall A" first="Aron J" last="Hall">Aron J. Hall</name><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name><name sortKey="Paden, Clinton R" sort="Paden, Clinton R" uniqKey="Paden C" first="Clinton R" last="Paden">Clinton R. Paden</name><name sortKey="Paden, Clinton R" sort="Paden, Clinton R" uniqKey="Paden C" first="Clinton R" last="Paden">Clinton R. Paden</name><name sortKey="Queen, Krista" sort="Queen, Krista" uniqKey="Queen K" first="Krista" last="Queen">Krista Queen</name><name sortKey="Tao, Ying" sort="Tao, Ying" uniqKey="Tao Y" first="Ying" last="Tao">Ying Tao</name><name sortKey="Tong, Suxiang" sort="Tong, Suxiang" uniqKey="Tong S" first="Suxiang" last="Tong">Suxiang Tong</name><name sortKey="Zhang, Jing" sort="Zhang, Jing" uniqKey="Zhang J" first="Jing" last="Zhang">Jing Zhang</name><name sortKey="Zhang, Jing" sort="Zhang, Jing" uniqKey="Zhang J" first="Jing" last="Zhang">Jing Zhang</name></country><country name="Australie"><noRegion><name sortKey="Shi, Mang" sort="Shi, Mang" uniqKey="Shi M" first="Mang" last="Shi">Mang Shi</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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